ISSN: 0970-938X (Print) | 0976-1683 (Electronic)

Biomedical Research

An International Journal of Medical Sciences


Synthesis and biological evaluation of tetrahydrobenzo[b]pyran derivatives as potential anti-ovarian cancer agents

The synthesis and characterization of four novel pyran derivatives (1-4) have been done by means of IR, 1H NMR, HRMS, and single crystal X-ray crystallography. The antitumor activities of the four compounds were studied in order to inhibit three human ovarian cancer cells, which are OVCAR, HRA and COC1, growth by MTT assay. It was found that compound 4 exerted much more potent activities against all of these cell lines than other compounds did.

Author(s): Chuan Wang
Abstract | Full-Text | PDF

Share this  Facebook  Twitter  LinkedIn  Google+