ISSN: 0970-938X (Print) | 0976-1683 (Electronic)

Biomedical Research

An International Journal of Medical Sciences

Abstract

Longitudinal changes in hematologic manifestations of HIV infection in the multicenter AIDS cohort study (MACS).

The most common cause of HIV disease throughout the world is HIV-I which was first iden-tified in West Africa. Since the first cases of AIDS were reported in 19811, more than 179,000 cases of AIDS have been reported in the United States and 113,000 (63%) of these patients have died2. This disease is now a leading cause of death among men and women un-der 45 years old and of children under 5 years. Hematological derangements and anaemia with a trend towards iron deficiency are common. The negative impact of anaemia concur-rent with established HIV infection upon morbidity and mortality has been well docu-mented but the prognostic potential and long-term effects of anaemia & other hematological changes during acute HIV-1 infection remain unknown.The aim of this study was to deter-mine if HIV status influences changes in iron levels and anaemic measurements and to re-late these to progression of disease as judged by CD4 T cell lymphocyte counts.

Author(s): Deepak Arora
Abstract | Full-Text | PDF

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