Biomedical Research

Objective: To analyse the pathogenic bacteria and risk factors for nosocomial infection in patients in department of urology as well as to guide the clinical control and treatment of patients with nosocomial infection in the department of urology.

Methods: 868 cases of patients in department of urology from 2011 to 2013 were chosen, of which the pathogen distribution and drug resistance of 92 cases of infected patients were analysed to study the risk factors for nosocomial infection in patients of department of urology.

Results: The nosocomial infection rate of patients in department of urology was 10.460%; the infected areas were mainly in urinary system, accounting for 39.413%, followed by reproductive system, surgical incision, respiratory system, respectively accounting for 23.491%, 17.439%, 13.405%; a total of 98 strains of pathogens were isolated, including 36 strains of gram positive bacteria accounting for 36.473%, and 62 strains of gram negative bacteria accounting for 63.427%; the resistance rate of the main gram positive bacteria to penicillin G and ampicillin were higher, and the resistance rate to acetazolamide was <6.400%. The resistance rate of the main gram negative bacteria to soil Kanamycin and erythromycin was higher with a low resistance rate of <4.40% to imipenem; greater age of patients, undergoing surgery, long time of hospitalization, application of catheter, association with other diseases, undergoing invasive operation and no use of antibiotics for prevention were the risk factors for patients with nosocomial infection in department of urology (P<0.405).

Conclusion: The incidence of nosocomial infection in department of urology is high, and the pathogen has certain resistance; clinical measures should be taken to control the occurrence of nosocomial infection in department of urology, and once infection occurs, antibiotic drugs with low resistance rate according to the results of drug sensitivity test should be chosen for timely treatment.

Author(s): Yu Sang, Ming Guo, Jindan Huang
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