ISSN: 0970-938X (Print) | 0976-1683 (Electronic)

Biomedical Research

An International Journal of Medical Sciences

The combined use of fat graft enriched with stromal vascular fraction cells and platelet-rich plasma in the treatment of breast soft tissue defect

Joint Event on 2nd International Conference on Tissue Science and Molecular Biology, Stem Cells & Separation Techniques
June 06-07, 2019 | London, UK

Pietro Gentile

University of Rome Tor Vergata, Italy

Posters & Accepted Abstracts : Biomed Res

Abstract:

The use of autologous fat grafting is ideal in breast reconstruction. However, published data on long-term outcomes and instrumental results of fat grafting to the breast are lacking. The purpose of this study was to review the authors�¢���� experience of fat grafting, evaluating the effects related to the use of enhanced stromal vascular fraction (e-SVF) and fat grafting with platelet-rich plasma (PRP) in the maintenance of fat volume in breast reconstruction, comparing the results with a control group. Twenty-three patients aged 19�¢����60 years affected by breast soft tissue defects were analyzed at the Plastic and Reconstructive Department of the University of Rome Tor Vergata. 10 patients were treated with SVF-enhanced autologous fat grafts and 13 patients were treated with fat grafting mixed with plateletrich plasma. The patients in the control group (n=10) were treated with centrifuged fat grafting injection according to Coleman�¢����s procedure. The patients treated with SVFenhanced autologous fat grafts showed a 63% maintenance of the contour restoring and of three-dimensional volume after 1 year compared with the patients of the control group treated with centrifuged fat graft, who showed a 39% maintenance. In those patients who were treated with fat grafting and PRP, we observed a 69% maintenance of contour restoring and of three-dimensional volume after 1 year. As reported, the use of either e-SVF or PRP mixed with fat grafting produced an improvement in maintenance of breast volume in patients affected by breast soft tissue defect.

Biography:

E-mail:

pietrogentile2004@libero.it

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