Hepatoid Variant of Pancreatic Cancer: Insights from a Case and Literature Review

Context “Hepatoid” cancer refers to an extrahepatic neoplasm with hepatocellular differentiation. The stomach is the mostcommon site and pancreatic origin is distinctly uncommon. Case report We describe a patient with hepatoid pancreatictumor who presented with inoperable metastatic disease. Conclusion Serum levels or tissue staining with alpha-fetoprotein(AFP) may not be a reliable tumor marker in these cases and an experienced pathologist and appropriateimmunohistochemical staining are essential for early diagnosis. This report incorporates a comprehensive literature reviewoutlining the clinical presentation, diagnostic difficulties, management and outcomes associated with this rare pathologicalentity.

Author(s):

Constantin A Dasanu, Shounak Majumder

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