Dermatoglyphics is the scientific study of fingerprints. Recently, interest has been developed in associating Dermatoglyphics with various diseases. Therefore, this study was undertaken to find the frequency of various fingerprint patterns in Type 2 diabetes mellitus (T2DM) with and without ischemic heart disease (IHD). This study also intended to find the frequency of finger print patterns in T2DM patients having the family history of cardiovascular disease. Twenty five T2DM male patients in the age group of 38-65 years were selected, of which 18 had ischemic heart disease (IHD) and 16 patients had the family history of cardiovascular events. The right hand fingerprints of patients were obtained on an A4 size paper. The papers were coded and analyzed for finger print patterns, based on IHD and family history after categorizing them into 4 groups. In T2DM patients, there was higher frequency of whorls than other patterns. This study observed that in T2DM patients with IHD exhibited less frequency of arches, high frequency of whorls and ulnar loops when compared with T2DM patients without IHD, but the difference was not statistically significant. Finger print patterns of patients with family history of cardiovascular disorders had high frequency of radial loop type of finger print pattern and lower frequency of arches. Dermatoglyphics in T2DM and in patients with family history of CVD, it did not show preponderance of any of the fingerprints in IHD. Therefore, dermatoglyphics may be T2DM but not in identifying the risk category for IHD.