This study is a descriptive study to investigate the degree of anxiety and depression and the frequency of major symptoms in liver cirrhosis patients and to confirm the correlation between them. In order to collect the data, a joint researcher visits the outpatient department of the gastric medicine and the ward from December 28, 2015 to September 30, 2016, the questionnaire was delivered and collected directly to the subjects. In patients with liver cirrhosis, the mean depression was 15.11, the anxiety was 11.46, and the symptom experience was 26.13, which was not significant. In the severity classification according to the Child-Push Score, Child A was significantly lower in depression than Children B and C. In the symptomatic experience, Child A was significantly lower than Children B and C, on the other hand, there was no significant difference between Children A-C in anxiety. The experience of disease symptom showed no significant correlation with anxiety and depression, anxiety and depression were positively correlated. Therefore, for effective symptom management for patients with liver cirrhosis, it is necessary to identify the severity of the disease and to provide nursing intervention accordingly. In addition, nursing intervention for patients with liver cirrhosis requires physical aspects as well as psychological nursing intervention.