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potential vanilloid 4 \(Trpv4\) inhibition protects mice against lipopolysaccharide stress.) /C [ 0 0 0 ] /A << /S /GoTo /D (_OPENTOPIC_TOC_PROCESSING_d74e197) >> /Parent 82 0 R /Prev 83 0 R >> endobj 85 0 obj << /Title (Abstract) /C [ 0 0 0 ] /A << /S /GoTo /D (_OPENTOPIC_TOC_PROCESSING_d74e221) >> /Parent 84 0 R /Next 86 0 R >> endobj 86 0 obj << /Title (Keywords:) /C [ 0 0 0 ] /A << /S /GoTo /D (_OPENTOPIC_TOC_PROCESSING_d74e244) >> /Parent 84 0 R /Prev 85 0 R /Next 87 0 R >> endobj 87 0 obj << /Title (Accepted on December 22, 2017) /C [ 0 0 0 ] /A << /S /GoTo /D (_OPENTOPIC_TOC_PROCESSING_d74e254) >> /Parent 84 0 R /Prev 86 0 R /Next 88 0 R >> endobj 88 0 obj << /Title (Introduction) /C [ 0 0 0 ] /A << /S /GoTo /D (_OPENTOPIC_TOC_PROCESSING_d74e262) >> /Parent 84 0 R /Prev 87 0 R /Next 89 0 R >> endobj 89 0 obj << /First 90 0 R /Last 98 0 R /Title (Material and Methods) /C [ 0 0 0 ] /A << /S /GoTo /D (_OPENTOPIC_TOC_PROCESSING_d74e292) >> /Parent 84 0 R /Prev 88 0 R /Next 99 0 R >> 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endobj 96 0 obj << /Title (Detection of apoptotic cells by TUNEL staining) /C [ 0 0 0 ] /A << /S /GoTo /D (_OPENTOPIC_TOC_PROCESSING_d74e373) >> /Parent 89 0 R /Prev 95 0 R /Next 97 0 R >> endobj 97 0 obj << /Title (F-actin staining and confocal microscopy) /C [ 0 0 0 ] /A << /S /GoTo /D (_OPENTOPIC_TOC_PROCESSING_d74e383) >> /Parent 89 0 R /Prev 96 0 R /Next 98 0 R >> endobj 98 0 obj << /Title (Statistical analysis) /C [ 0 0 0 ] /A << /S /GoTo /D (_OPENTOPIC_TOC_PROCESSING_d74e394) >> /Parent 89 0 R /Prev 97 0 R >> endobj 99 0 obj << /First 100 0 R /Last 103 0 R /Title (Results) /C [ 0 0 0 ] /A << /S /GoTo /D (_OPENTOPIC_TOC_PROCESSING_d74e405) >> /Parent 84 0 R /Prev 89 0 R /Next 104 0 R >> endobj 100 0 obj << /Title (HC067047 enhanced the apoptosis in 12.5 mg/kg lps-induced mice, but attenuated in 50 mg/kg lps-induced mice) /C [ 0 0 0 ] /A << /S /GoTo /D (_OPENTOPIC_TOC_PROCESSING_d74e525) >> /Parent 99 0 R /Next 101 0 R >> endobj 101 0 obj << /Title (TRPV4 expressions increased in 12.5 or 50 mg/kg lps-induced mice, but did not change with or without hc067047 treatment) /C [ 0 0 0 ] /A << /S /GoTo /D (_OPENTOPIC_TOC_PROCESSING_d74e535) >> /Parent 99 0 R /Prev 100 0 R /Next 102 0 R >> endobj 102 0 obj << /Title (HC067047 enhanced the apoptosis in trpv4 normal expression cells, but attenuated the apoptosis in the trpv4 over expression cell\ s) /C [ 0 0 0 ] /A << /S /GoTo /D (_OPENTOPIC_TOC_PROCESSING_d74e554) >> /Parent 99 0 R /Prev 101 0 R /Next 103 0 R >> endobj 103 0 obj << /Title (HC067047 suppressed lps-induced actin depolymerization) /C [ 0 0 0 ] /A << /S /GoTo /D (_OPENTOPIC_TOC_PROCESSING_d74e713) >> /Parent 99 0 R /Prev 102 0 R >> endobj 104 0 obj << /Title (Discussion) /C [ 0 0 0 ] /A << /S /GoTo /D (_OPENTOPIC_TOC_PROCESSING_d74e723) >> /Parent 84 0 R /Prev 99 0 R /Next 105 0 R >> endobj 105 0 obj << /Title (Conclusion) /C [ 0 0 0 ] /A << /S /GoTo /D (_OPENTOPIC_TOC_PROCESSING_d74e747) >> /Parent 84 0 R /Prev 104 0 R /Next 106 0 R >> endobj 106 0 obj << /Title (Acknowledgements) /C [ 0 0 0 ] /A << /S /GoTo /D (_OPENTOPIC_TOC_PROCESSING_d74e757) >> /Parent 84 0 R /Prev 105 0 R /Next 107 0 R >> endobj 107 0 obj << /Title (References) /C [ 0 0 0 ] /A << /S /GoTo /D (_OPENTOPIC_TOC_PROCESSING_d74e766) >> /Parent 84 0 R /Prev 106 0 R /Next 108 0 R >> endobj 108 0 obj << /Title (*Correspondence to) /C [ 0 0 0 ] /A << /S /GoTo /D (_OPENTOPIC_TOC_PROCESSING_d74e1354) >> /Parent 84 0 R /Prev 107 0 R >> endobj 109 0 obj <>>>endobj 110 0 obj <>stream xUn0 >endobj 112 0 obj <>stream x|TE?|{&Mْ $$K DERE("]" * "lbA*<""c=?dwܹSΜ9s$;00rZJyPuk=:=xa㦌l W^?nLaQc=ڝN̸DOpյ3 =*fȕ/R\UW1%' )T&BB 9dB<[MX'C L`+Z-)QM=`\ a!lюGAhȦ6Mc{%)pnx+pQ/ xbai|^)T9@qP{ZGP=Vxa 2&30fZ{=/PqZx7>/;T֑uZ'ħ[]nmOq Wx*o˫ah-a"@#S\ T6)*/('u:EVEcxEg~OHn NIwN}Z|N(1X7^X᝸ 84j{.Ql,AvZi<=0>_M}sf64j$7{FC\\E?:r^e[MP+Mꗚi S0[P=\4f#f JHD\4+~Rqϩm%囪OS_Y*R!m ;,^dBȯV^g)(iiv ak8׸ &yw$ov8 gq| ΁z&Ј=$P f1F~>cUHVЈn8J{n(2Io*i͢" r6@Vvj'q$ iң~U]%0ef$%P\.n"]RH 1pie z,Y\G3(g |h^ w ,pB,U6+;g}jk$Kfrx_@cho2v 8NZG% 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