Introduction: Epilepsy is one of the most common neurological disorders which can occur in any age, strain, and social classes. Seizures can effect on daily life of infants and adolescents and can have a considerable effect on presence in school, society, participating in social activities and performing of especial sports at the school. Therefore, the aim of the present study was to accurate determining and investigating of life quality on function of children with epilepsy. Method: The present study was performed prospectively and cross sectional on patients with epilepsy referring to Ahvaz Golestan Hospital. All data about the disease will be collected verbally with presence of interviewer and patient's family. The questionnaire of child epilepsy (parent's form) CEQ-P was used in order to evaluate the quality of life (QOL). Results: The average of seizures during the last month was 6.4 ± 10.8 times, the results showed that the average of cognitive function in patients was significantly higher than mean score of 50 (p>0.001). on the other hand, the mean score of emotional function, social function and physical function were 46.03 ± 14.85, 33.50 ± 33.75, and 41.57±24.95, respectively which were significantly higher than the mean score of 50 (p=0.001), and finally, the results showed that the total mean score of life quality which was 38.52 ± 18.29 was significantly higher than the mean score of 50 (p<0.001). Conclusion: The results of survey showed that epilepsy has a negative effect on various aspects of life quality of children. We can endeavor with performing appropriate approaches to improve it with recognizing the life quality and trying to improving of life quality and with paying attention to its various aspects.