To analyze and evaluate perioperative characteristics in gynecological patients complicated with rheumatic diseases, 34 gynecological patients complicated with rheumatic diseases who received surgical treatment in the Second Hospital of Shanxi Medical University from January 2002 to October 2012 were selected as study group, and 34 patients with similar- gynecological diseases served as control group. Preoperative erythrocyte sedimentation rate (ESR), average operation time, average amount of intraoperative bleeding and postoperative complications in all patients were analyzed retrospectively. There were significant changes in the preoperative ESR in the study and control group(19.97±11.97 mm/H vs. 9.91±2.02 mm/H). There were no significant differences in the average operation time or average amount of intraoperative bleeding (P>0.05), but the incidence of postoperative complications was significantly higher in the study group (29.41%) than the control group (5.88%) (P < 0.05). Gynecological patients complicated with rheumatoid disease can tolerate gynecological surgery, but patients with increased preoperative ESR have a greater risk for postoperative infections.