Biomedical Research

Objective: To explore the effect of dual-band semiconductor laser transurethral resection of prostate on efficacy, stress response and quality of life in patients with Benign Prostatic Hyperplasia (BPH).

Methods: 126 cases of patients with benign prostatic hyperplasia treated in our hospital during January 2014 to January 2015 were randomly divided into observation group and control group, with 63 cases in each. Patients in control group were treated with Transurethral Resection of Prostate (TURP). Patients in observation group were treated with Dual-Band Semiconductor Laser Transurethral Resection of Prostate (DBSCLTURP). The surgical indications, change of maximum urinary flow rate, post-voiding residual urine volume, IPSS score, BI index scores, quality of life before surgery and 3 months after surgery, as well as serum Cor and E levels before and 7 days after surgery were compared.

Results: Blood loss, postoperative indwelling catheter time, postoperative bladder irrigation time, postoperative hospital stay and postoperative complications in observation group were better than that in control group (p<0.05). In both groups maximum urinary flow rate significantly increased after 3 months, and post-voiding residual urine volume decreased significantly (P<0.05). Maximum urinary flow rate in observation group was higher than the control group 3 months after surgery, and postvoiding residual urine volume lower than the control group (P<0.05). Levels of serum Cor and E increased significantly 7 days after surgery in both groups, but with smaller extent of increase in observation group (P<0.05). In observation group serum Cor, E level was lower than the control group 7 days after surgery (P<0.05). In both groups, IPSS score decreased significantly after 3 months, while the BI index score increased significantly after 3 months (P<0.05). In observation group, IPSS score after 3 months was significantly lower than the control group, and the BI index scores after 3 months was higher (P<0.05). In observation group, bodily pain, mental health, physical function, physical occupation, emotional function, social function, vitality, general health after 3 months were better than the control group (P<0.05).

Conclusion: The effect of dual-band semiconductor laser transurethral resection of prostate in patients with benign prostatic hyperplasia was significant, with little effect on the stress response. It can significantly improve the quality of life of patients, with important research value.

Author(s): Cheng Liu, Xuejun Liu, Duo Liu, Jiagui Mu, Dongsheng Zhu, Li Fan, Qun Song, Dongwei Yao
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