ISSN: 0970-938X (Print) | 0976-1683 (Electronic)

Biomedical Research

An International Journal of Medical Sciences

All submissions of the EM system will be redirected to Online Manuscript Submission System. Authors are requested to submit articles directly to Online Manuscript Submission System of respective journal.

Abstract

Clinical and pathological features of three types of peritoneal tuberculosis: a single centre in China

Background: Tuberculosis (TB) is a crucial communicable disease worldwide. Peritoneum tuberculosis (TBP) is a common type of extra-pulmonary tuberculosis.

Aim: To investigate clinicopathological features of three different types of TBP. Methods: This retrospective, observational study was conducted from 2009 to 2014 in the hospitalized patients with TBP. Based on the clinical data and surgical records, patients were divided into: wetascitic, fibrotic-fixed, and dry-plastic types. Categorical data were analysed using the Chi-square test or a two-tailed Fisher's exact test.

Results: Of the 91 patients (50 male, 41 femalemale to female ratio=1.22) enrolled, 48 (52.7%) were wetascitic, 33 (36.3%) were fibrotic-fixed and 10 (11.0%) were dry-plastic types. The frequency of haematogenous dissemination of pulmonary TB was significantly higher in the dry-plastic type than in fibrotic-fixed type (P=0.0498). The frequency of abdominal pain was significantly lower in the wet-ascitic than in the other two types (P=0.000 and P=0.017). Patients (30 (90.9%)) of fibrotic-fixed type had ileus. The Langhans giant cells were observed more in the wet-ascitic type than in fibrotic-fixed type (P=0.006). All slices in the dry-plastic type were observed with granulomatous inflammation (P=0.040). The hospital stay prolonged in the fibrotic-fixed type and the dry-plastic type than the wet-ascitic type (P=0.006 and P=0.003).

Conclusion: The fibrotic-fixed and dry-plastic types TBPs presented more rate of abdominal pain. Most of the fibrotic-fixed type patients have ileus. The Langhans giant cells were observed more in the wetascitic type. All specimens of the dry-plastic type were observed with granulomatous inflammation. All dry-plastic type could be diagnosed through histopathology, but fibrotic-fixed type could not.


Author(s): Chaohui Zhu, Shuli Liu, Junshan Zhai, Zhi Chen, Kai Wu, Nan Li

Abstract | Full-Text | PDF

Share this  Facebook  Twitter  LinkedIn  Google+