Objectives: The objective of the study was as follows: To determine impact of work duration on musculoskeletal disorders in sugarcane factory workers. Methods: Ethical clearance was obtained from the institutional ethical committee. A total of 74 sugarcane factory workers were assessed and all were included in this study based on inclusion criteria, Informed consent was taken and the workers were explained how their bad working conditions lead to musculoskeletal disorders and they were explained that this study helped us to find minimum duration which lead to musculoskeletal disorders and the data was collected using occupational health and safety standard questionnaire and Nordic musculoskeletal disorder questionnaire. Results: This study found that duration for development of minimum complaints is within 1-5 years. Conclusion: We found that average duration for development of minimum complaints start appearing within 1-5 years’ work experience (1-1825 days) but maximum musculoskeletal disorders in sugarcane factory workers occur after a duration of 16-20 years (5476-7300 days) of work experience. The musculoskeletal disorders which appears with minimum duration of 1-5 years initiates with neck pain followed by low back pain. The musculoskeletal disorders which occurs after maximum duration of work are neck pain, low back pain which increases with increased duration of work and with increased duration it leads to gradually increased complaints like shoulder pain, elbow pain, upper back pain, hip pain, knee pain and ankle pain.